Description
Dual-Agonist Ligand | CAS 2023788-19-2
“These Statements Have Not Been Evaluated By The Food And Drug Administration. This Product Is Not Intended To Diagnose, Treat, Cure Or Prevent Any Disease.”
TECHNICAL SPECIFICATIONS
- Product Ref : Tirz 75 (High-Mass Reagent)
- Chemical Class : Dual-Agonist Peptide Ligand
- CAS Number : 2023788-19-2
- Molecular Formula : C₂₂₅H₃₄₈N₄₈O₆₈
- Molecular Weight : ~4813.53 g/mol
- Sequence Length : 39 Amino Acids
- Format : Lyophilized Filtered Cake
- Mass Format : High-Mass Unit (75)
- Purity : ≥99% (RP-HPLC Verified)
- Solubility : Soluble in BAC Water / Buffer
- Storage : -20°C (Desiccated)
Disclaimer : For Research Use Only (RUO). Not for human use.
This product comprises a High-Mass Unit (75 Format) of the synthetic peptide ligand known as Tirz. It is a linear 39-amino acid chain that functions as a Dual-Agonist, targeting two distinct incretin receptor pathways simultaneously.
Unlike standard low-mass units often limited to single-assay use, this High-Mass Format is engineered for high-throughput laboratories. It allows researchers to create a concentrated Stock Solution, ensuring that every cellular culture or study model in a study receives an identical chemical concentration.
Research Mechanism: In 2026-era metabolic research, this ligand is utilized to study:
- Synergistic Signaling : How activating the GIP receptor alongside the GLP-1 receptor alters cellular energy homeostasis.
- Lipid Substrate Utilization : Investigating how dual-pathway modulation influences adipocyte (fat cell) metabolism in vitro.
- Receptor Kinetics : Measuring binding affinity without the interference of insulinogenic feedback loops.
- Synergistic Mechanism of Action : Distinct from mono-target ligands, Tirz exhibits simultaneous affinity for both GIP and GLP-1 recognition sites. This dual-receptor occupancy modulates intracellular cAMP flux, facilitating the investigation of synergistic signaling pathways in isolated cell cultures.”
REGULATORY & COMPLIANCE STATEMENT (RUO)
Regulatory Classification & Usage Disclaimer :
This product is strictly classified as a Research Use Only (RUO) reagent.
Chemical Reference Standard: It is supplied solely for in-vitro testing and laboratory calibration.
Not a Drug : This compound has not been evaluated by the FDA for safety or efficacy in humans.
Handling Protocol : This reagent is a potent biological modulator. Researchers must wear appropriate PPE (gloves, eyewear) during reconstitution and handling.
Safety Data : Refer to CAS 2023788-19-2 safety sheets before use.
Strict Prohibition : Any intent to use this product for bodily introduction (injection/ingestion) is a violation of federal compliance protocols.
