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⚠ Product Usage: For Research Use Only – Not for Human or Veterinary Use

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GLP-3R (Reta) Triple Agonist GIP GLP-1 and GCG receptors

Price range: $49.00 through $899.00

Bacteriostatic water needed for reconstitution. Bacteriostatic water is not included; please order separately.

Reta Research Grade (RUO) (CAS 2381089-83-2, LY3437943) is a 39–amino acid unimolecular peptide designed as a triple agonist for GIP / GLP-1 / Glucagon (GCG) receptors. Supplied as a lyophilized white powder with ≥99% purity (HPLC verified) and endotoxin <1.0 EU/mg, it is soluble in sterile or bacteriostatic water.

The molecule includes a C20 fatty diacid moiety for albumin binding and extended stability (reported ~6-day half-life), supporting metabolic, obesity, T2D, and hepatic defatting research models.
For Research Use Only (RUO). Not for human or veterinary use.

Earn up to 899 points.

⚠ Product Usage: For Research Use Only – Not for Human or Veterinary Use

10peptides products are supplied to qualified research professionals and institutional users for in vitro laboratory research only. KYC verification is required prior to order fulfillment, and we reserve the right to refuse orders that do not meet buyer qualification criteria. These products are not drugs, foods, cosmetics, or dietary supplements, have not been evaluated by the FDA, and are not intended for human or animal use. Any such use is prohibited and may violate federal, state, or local law. By purchasing, the buyer represents and warrants that the product will be used solely for in vitro research.

Technical Specifications

Molecular Data
Product Ref
Reta
CAS Number
2381089-83-2
Chemical Class
incretin mimetic
Molecular Weight
4731.33 g/mol
Sequence Length
39 Amino Acids
Format
mg
Mass Format
5-60
Purity
Greater than 99%
Solubility
Lyphodized powder solubal in bacteriostatic water or sterile water
Storage
Lyophilized Powder: Store at \(-20^{\circ }\text{C}\) to maintain stability for up to \(24\) months.Reconstituted Solution: Once dissolved, it should be stored refrigerated at \(4^{\circ }\text{C}\) and used within \(4\) weeks. It is crucial to avoid repeated freeze-thaw cycles
Intended Use
In vitro (in glass) lab use only. Not for human or animal use

Product Description

“These Statements Have Not Been Evaluated By The Food And Drug Administration. This Product Is Not Intended To Diagnose, Treat, Cure Or Prevent Any Disease.”
Product Specifications
  • Product Name : Reta (Research Grade)
  • CAS Number : 2381089-83-2
  • Common Name : LY3437943
  • Molecular Formula : C221H342N46O68
  • Molecular Weight : 4731 g/mol
  • Peptide Type : Triple-Hormone Receptor Agonist
  • Target Receptors : GIP / GLP-1 / Glucagon (GCG)
  • Purity : ≥99% (HPLC Verified)
  • Form : Lyophilized White Powder
  • Solubility : Soluble in sterile water or bacteriostatic water
  • Endotoxin Level : Less than 1.0 EU/mg

Disclaimer : For Research Use Only (RUO). Not for human use.

Reta is a synthetic unimolecular peptide comprising 39 amino acids. Unlike dual agonists, it integrates activity at the Glucagon Receptor (GCGR) alongside GIP and GLP-1, creating a “Triple Synergy”.

 

Structure-Activity Relationship (SAR): The backbone is derived from GIP but modified to introduce Glucagon activity. It features a C20 fatty diacid moiety that binds to albumin, protecting the peptide from enzymatic degradation and extending its half-life to approximately 6 days.

 

Tuned Potency: Reta is designed with a specific hierarchy of potency: highest at GIP (for lipid buffering), moderate at GLP-1 (for satiety), and carefully tuned at Glucagon (to drive energy expenditure without hyperglycemia)

Regulatory & Compliance Statement

 

FDA Status : Reta is currently an Investigational New Drug (IND) in Phase 3 clinical trials (TRIUMPH & TRANSCEND series). It is not FDA-approved.

 

WADA Status : Prohibited under S2 (Peptide Hormones).

 

Usage : Strictly for Laboratory Research Use Only (RUO). Not for human use, diagnostic, or clinical procedures.

 

Potential Research Application

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The products on this website are for legitimate research use only. They are not intended to prevent, treat, or cure any illness or disease and are not intended for human consumption. By accessing this site, you acknowledge that you are at least 21 years of age, understand these terms, and have a legitimate research basis for buying these products

NOTE: All of our compounds are sold individually, and DO NOT include research supplies such as syringes. Most are sold in powder form and require reconstitution with a suitable diluent solution prior to research.