Description
“These Statements Have Not Been Evaluated By The Food And Drug Administration.
This Product Is Not Intended To Diagnose, Treat, Cure Or Prevent Any Disease.”
Sermorelin Acetate (RUO) | GHRH 1-29 Agonist | ≥99% Purity
Prodcut Specification
- Product Name : Sermorelin Acetate (Research Grade)
- CAS Number : 86168-78-7
- Synonyms / Common Names : Sermorelin acetate hydrate 114466-38-5 AKOS040744848
- Molecular Formula : C151H252N44O45S
- Molecular Weight : 3436.0 g/mol
- Peptide Type : Growth Hormone-Releasing Hormone (GHRH) Agonist
- Target Receptor : GHRH Receptor (GHRHR)
- Purity : ≥99% (HPLC Verified)
- Form : Lyophilized White Powder
- Solubility : Soluble in bacteriostatic water or sterile water
- Endotoxin Level : Less than 1.0 EU/mg
Disclaimer : For Research Use Only (RUO). Not for human use.
Chemical Identity & “Survivor” Status
Sermorelin (GRF 1-29) is a synthetic polypeptide comprising the first 29 amino acids of endogenous human GHRH. Unlike newer synthetic peptides that have faced regulatory bans, it possesses a unique “Safe Harbor” status in the USA.
Structural Efficiency : It contains the full biological activity of GHRH within the N-terminal 29-amino acid sequence, making it highly specific to the GHRH receptor.
Regulatory Resilience : Because it is the active ingredient of a formerly FDA-approved drug (Geref) that was not withdrawn for safety reasons, it remains the “Last Peptide Standing” for compliant research into the somatotropic axis.
Preservation of Physiology : Unlike exogenous hormones, It stimulates the anterior pituitary to secrete growth hormone in a pulsatile manner.
Chemical structure of Sermorelin Acetate (GRF 1-29)

Verified 2D chemical structure of Sermorelin Acetate (GHRH 1-29) peptide (CAS 86168-78-7) showing the biologically active N-terminal fragment for pituitary research.
This synthetic 29-amino acid peptide retains the full biological activity of endogenous GHRH, optimized as an acetate salt for stability and solubility in research protocols.
The Physiological Advantage: Sermorelin vs. rhGH vs. Reta
It is distinct because it works with the body’s natural feedback loops, specifically the inhibitory control of somatostatin.




